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Epitope Mapping: A Practical Approach (Practical Approach Series)

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 | #4525469 in Books |  2001-03-15 | Original language:English | PDF # 1 |  9.30 x.70 x7.10l,1.45 | File type: PDF | 304 pages

|| ||"For researchers who need to define the regions of antigens that make contact with the antigen-binding site of antibodies or T- cell receptors, specialists explain the epitope mapping technique, which can also be adapted to identify regions on other ligands i

Epitope Mapping covers all the major methods for the identification and definition of epitopes. The Pepscan assay is used to define B cell epitopes and makes use of synthetic peptides but can only be used if the amino acid sequence is known. It can be adapted for the delineation of both helper T cells and cytotoxic T cells. The identification of combined B and T cell epitopes can also be achieved using synthetic peptides. There are other methodologies for analys...

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